Standing up from your desk chair—a task you barely think about—can suddenly feel challenging after long hours at work. For many office workers, moving from sitting to standing brings unexpected stiffness, achy knees, or a nagging joint pain. This discomfort breaks up your workflow and can make everyday movement feel like an uphill battle. In fact, musculoskeletal aches and pains are common among adults in office environments, often affecting both comfort and productivity. One workplace study found that "body part discomfort decreased by an average of 62 percent" after simple ergonomic changes , underscoring how sitting too much can drive physical complaints (Nerhood & Thompson, 1994). Thankfully, there are new solutions like Arthrosamid ®, a minimally invasive injection designed to ease joint pain . When combined with healthy work habits and gentle movement , Arthrosamid ® can help make those daily sit-to-stand motions far more comfortable.

Why Sit-to-Stand Movements Can Cause Discomfort in Office Workers

Getting up from your chair is surprisingly complex—it requires your muscles and knees to work together in a smooth, coordinated motion. Ideally, your quadriceps , hips, and core all help lift your body. But when you've been sitting for hours, these muscles can weaken or become less responsive, forcing your knee joints to absorb more stress than they should.

That extra stress can leave your knees feeling stiff and sore, especially if you spend most of your day at your desk. A sedentary lifestyle is linked to poorer joint health and can speed up the onset of knee discomfort . Even small factors—like your posture on the commute or how you walk around the city—can add up to strain your knees further. This is why both medical interventions and simple lifestyle changes are important for minimizing that sit-to-stand pain .

How Does Arthrosamid® Work?

Arthrosamid ® is an innovative gel injection made from polyacrylamide hydrogel —a safe, water-rich material. When injected directly into the knee joint , the gel binds to the joint’s lining (the synovial membrane) and thickens it, creating a soft, cushioning scaffold.

Think of Arthrosamid® as adding a protective layer that improves the joint’s natural lubrication and reduces friction between bones. Because your body doesn’t break it down quickly, Arthrosamid ® provides ongoing support for one to two years. Studies show it can significantly relieve pain and improve joint function for many people, although it isn’t a cure and results will vary.

What Does the Research Say About Arthrosamid® for Office Workers?

Clinical studies on Arthrosamid ® have focused on adults who are often similar to office workers—generally older, without complex conditions like diabetes . Over a 24-month period, patients reported substantial pain relief and improvements in using their knee joints, using standard scales like the Visual Analogue Scale (VAS).

Research has found that those with less severe knee damage —measured on X-rays using the Kellgren–Lawrence grading system—tend to benefit even more from treatment. Notably, Arthrosamid ® is just as effective as other well-known injections, like hyaluronic acid or corticosteroids, and may have longer-lasting benefits for some people. Clinical trials also show a reliable safety record, with no persistent or serious side effects observed.

Maximizing Relief: Daily Habits to Pair with Arthrosamid®

While Arthrosamid® injections can provide valuable relief, combining them with smart everyday habits is the best way to protect your knee health and extend your results. Try stretching lightly before you stand or adding “warm-up” movements as you transition from desk to steps. Increasing your movement throughout the day—even in small ways—makes a big difference.

Maintain good posture when commuting and consider taking short walks during or after the workday to keep your joints healthy. Ergonomic tweaks like adjusting your chair height, alternating between sitting and standing, or wearing supportive shoes can also help prevent stiffness and keep discomfort at bay. In one workplace study, departments that adopted height-adjustable desks even saw improved productivity (Nerhood & Thompson, 1994). When combined, these daily habits and medical treatments help you move more comfortably all day.

Expert Care from Professor Paul Lee and MSK Doctors

Professor Paul Lee is an experienced orthopaedic specialist dedicated to musculoskeletal rehabilitation and personalized, patient-centered care. At MSK Doctors , you have access to state-of-the-art facilities and a multidisciplinary team ready to support your well-being.

While Professor Lee and his team did not develop Arthrosamid® , they are highly experienced in delivering this treatment and guiding patients through recovery plans tailored to individual needs—including ergonomic adjustments and rehabilitation.

Conclusion and Disclaimer
Arthrosamid ® injections offer an innovative, minimally invasive option for office workers struggling with knee discomfort during sit-to-stand movement. By cushioning and supporting knee joints, Arthrosamid ® relieves pain and improves everyday mobility. For long-lasting results, blend this treatment with good ergonomic habits and regular gentle movement. If persistent knee discomfort is impacting your work life, talk to your healthcare provider about Arthrosamid® and strategies to protect your joint health.

Always consult a qualified healthcare professional for personalized medical advice.