Arthrosamid® for Knee Osteoarthritis: Long-Lasting Relief and Improved Mobility Without Surgery

Miss Sophie Harris
Miss Sophie Harris
Published at: 7/10/2025

Arthrosamid® for Knee Osteoarthritis: Long-Lasting Relief and Improved Mobility Without Surgery

Living with Knee Osteoarthritis: Everyday Challenges

For millions of people, knee osteoarthritis turns simple daily activities into a challenge—whether it’s waking up with stiff joints, feeling pain when standing, or struggling with stairs. These symptoms don’t just limit movement; they can affect every part of life, from shopping and chores to staying active with family. Understandably, many people are looking for pain relief that lasts, but would prefer to avoid surgery. Arthrosamid ® offers a new, non-surgical approach designed to cushion the knee joint , ease pain, and help restore freedom of movement. In this article, we’ll break down what knee osteoarthritis is, how Arthrosamid works, the real benefits people have seen, and what you should consider if you’re thinking about this treatment.

What Is Knee Osteoarthritis and How Does It Affect You?

Knee osteoarthritis is a common condition where the smooth cartilage that covers the ends of your knee bones gradually wears down. As the cartilage thins out, bones begin to rub against each other, which leads to pain, swelling, and stiffness—especially after periods of rest or inactivity. The lining of the joint, known as the synovium, often becomes inflamed too, making movement even more difficult and uncomfortable.

Doctors often recommend lifestyle changes like regular exercise and weight management to help with symptoms. Pain relief might also come from medications or special injections called viscosupplements, which lubricate the joint. Unfortunately, these options often bring only short-lived relief for many people. That’s why there’s a growing need for treatments that do more than mask the pain —they help improve joint function in lasting ways.

How Does Arthrosamid® Work to Protect Your Knee?

Arthrosamid ® is an innovative gel made from 2.5% polyacrylamide hydrogel that is injected directly into the knee joint in a quick, minimally invasive procedure . It works in two main ways: restoring the thickness and smoothness of your joint fluid so that joints glide more easily, and integrating into the joint tissues to act as a protective, cushioning scaffold.

Clinical studies have found Arthrosamid to be both safe and effective, with no long-term side effects reported. Many people experience clear pain relief within weeks, and benefits can last for a year or more after a single injection. The procedure is performed under local anaesthetic with ultrasound guidance for precise placement, so it’s convenient and straightforward—typically done as an outpatient visit.

Real-Life Improvements: More Comfort and Easier Movement

People who receive Arthrosamid often notice real changes in their daily lives. They may find that morning stiffness eases sooner, walking feels smoother, and everyday actions like climbing stairs or doing chores become much less daunting. Not only does it help reduce pain, but Arthrosamid often empowers people to move more freely and enjoy a better quality of life.

The benefits are more than just temporary. Several studies have shown that improvements in comfort and mobility can last for over a year, with significant positive effects still seen at 52 weeks and beyond. Most people tolerate the injection very well, with only mild, short-lived discomfort around the knee . Although further long-term research is ongoing, current evidence suggests Arthrosamid is a safe and promising option for people struggling with knee osteoarthritis .

Expert Care with Professor Paul Lee and MSK Doctors

At MSK Doctors, patients benefit from the expertise of Professor Paul Lee —an experienced orthopaedic and rehabilitation specialist. The team uses advanced ultrasound imaging to guide every Arthrosamid injection , ensuring the gel is delivered precisely where it’s needed. This combination of cutting-edge technique and professional care helps maximise your chance of the best possible outcome.

Prior to treatment, each patient undergoes a thorough assessment to ensure their care plan is fully personalised. After the injection, MSK Doctors offer structured rehabilitation to help you recover and maintain your improved mobility. This whole-person approach means you’re supported every step of the way, not only during the injection but throughout your journey to better knee health.

Considering Arthrosamid®? What You Need to Know Next

Living with knee osteoarthritis isn’t easy, but new treatments like Arthrosamid are making long-lasting pain relief and better mobility possible without surgery. Supported by solid clinical research and delivered by expert medical teams, Arthrosamid is helping many people rediscover comfort in their daily lives.

If you think Arthrosamid might be right for you, talk with your healthcare provider about your options. Every knee and every individual is unique, so outcomes can vary. A personalised discussion with your doctor will help you decide if Arthrosamid fits into your treatment plan.

For individual medical advice, please consult a qualified healthcare professional.

This article is designed to offer easy-to-understand information about Arthrosamid and its role in managing knee osteoarthritis —making it simple to explore your options and make confident choices about your care.

References

Cole, A., Maulana, R. K., Whitehead, J. P., & Lee, P. Y. F. (2022). A Systematic Review of the Novel Compound Arthrosamid Polyacrylamide (PAAG) Hydrogel for Treatment of Knee Osteoarthritis. Medical Research Archives, 10(8). https://doi.org/10.18103/mra.v10i8.2950

Frequently Asked Questions

  • People with knee osteoarthritis often struggle with joint pain, stiffness and swelling, making daily activities like walking, climbing stairs and household chores difficult. These symptoms can impact mobility and overall quality of life, especially in the mornings or after periods of rest.
  • Arthrosamid® is a polyacrylamide hydrogel injected into the knee to cushion the joint and restore fluid thickness. At MSK Doctors, this minimally invasive procedure helps reduce pain and improve mobility, all under the care of skilled specialists using advanced ultrasound guidance.
  • Professor Paul Lee is a highly experienced orthopaedic and rehabilitation specialist at MSK Doctors. He uses advanced imaging and precise, personalised techniques to maximise safety and effectiveness, ensuring every Arthrosamid® injection is tailored to the patient’s needs for optimal outcomes.
  • Patients usually report reduced pain, less morning stiffness and easier movement in daily activities. Many find substantial improvements in mobility and comfort, with benefits that can last beyond a year. MSK Doctors also supports recovery with structured rehabilitation following treatment.
  • MSK Doctors deliver care with a focus on personalisation, expert ultrasound-guided injections and ongoing rehabilitation. Patients benefit from a whole-person approach, the expertise of Professor Paul Lee, and state-of-the-art facilities dedicated to non-surgical joint pain solutions.

Legal & Medical Disclaimer

This article is written by an independent contributor and reflects their own views and experience, not necessarily those of MSK Doctors. It is provided for general information and education only and does not constitute medical advice, diagnosis, or treatment.

Always seek personalised advice from a qualified healthcare professional before making decisions about your health. MSK Doctors accepts no responsibility for errors, omissions, third-party content, or any loss, damage, or injury arising from reliance on this material.

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