Advancing Joint Care: How Tailored Sulfation and Targeted Hydrogels Are Shaping Next-Generation OA TreatmentsOsteoarthritis (OA) affects millions worldwide, causing pain and reduced mobility. Recent advances in treatment focus on tailored sulfation and smart hydrogels, offering personalized and more effective therapies. Smart hydrogels mimic natural cartilage, providing mechanical support, biochemical customization, and intelligent drug delivery systems that respond to joint conditions. Tailored sulfation modifies…Osteoarthritis (OA) affects millions worldwide, causing pain and reduced mobility. Recent advances in treatment focus on tailored sulfation and smart hydrogels, offering personalized and more effective therapies. Smart hydrogels mimic natural cartilage, providing mechanical support, biochemical customization, and intelligent drug delivery systems that respond to joint conditions. Tailored sulfation modifies cartilage components to promote regeneration and reduce inflammation. Scaffold structures...