Structure Protection in Osteoarthritis: Evidence from Imaging and Clinical TrialsOsteoarthritis management is evolving from symptom relief to protecting joint structure, aiming to slow or reverse cartilage damage. Advances in MRI enable precise visualization of cartilage volume and joint space width, key indicators of disease progression. Clinical trials reveal that viscosupplementation with hyaluronic acid and chondroitin sulfate not only reduces…Osteoarthritis management is evolving from symptom relief to protecting joint structure, aiming to slow or reverse cartilage damage. Advances in MRI enable precise visualization of cartilage volume and joint space width, key indicators of disease progression. Clinical trials reveal that viscosupplementation with hyaluronic acid and chondroitin sulfate not only reduces pain but also improves joint mobility and preserves cartilage, offering long-term benefits. Despite challenges in interpreting im...