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The Connection Between Chronic Inflammation and Bone LossChronic inflammation, common in conditions like rheumatoid arthritis and lupus, significantly impacts bone health by accelerating bone loss and increasing osteoporosis risk. This article explores the mechanisms behind bone resorption versus formation imbalance due to inflammatory cytokines, and the role of glucocorticoids in exacerbating bone density reduction. Rheumatoid arthritis, inflammatory…Chronic inflammation, common in conditions like rheumatoid arthritis and lupus, significantly impacts bone health by accelerating bone loss and increasing osteoporosis risk. This article explores the mechanisms behind bone resorption versus formation imbalance due to inflammatory cytokines, and the role of glucocorticoids in exacerbating bone density reduction. Rheumatoid arthritis, inflammatory bowel disease, lupus, and psoriasis are highlighted for their contribution to bone health deterioration. The article also discusses prevention strategies, including a diet rich in calcium and vitamin D, weight-bearing exercises, regular bone density testing, and medication options like bisphosphonates. Minimising glucocorticoid use is crucial for managing bone health. For those with chronic inflammatory conditions, understanding these connections and implementing protective measures can help maintain stronger bones. Discover more about managing bone health amid chronic inflammation at MSK Docto
