Search Filters
Specialties
Cartilage
Specialties
Genetics
Specialties
Joint Preservation
Clear All
Search
Specialties
Cartilage
Specialties
Genetics
Specialties
Joint Preservation
287 results found in 4ms
Knee cartilage repair versus stem cell therapy
avatar
Miss Sophie Harris
13/8/2026
Knee cartilage repair versus stem cell therapy
Established cartilage repair using autologous chondrocytes shows 10–17 year durability for focal knee defects; mesenchymal stem cell therapies have not been tested in large-scale trials against them.Established cartilage repair using autologous chondrocytes shows 10–17 year durability for focal knee defects; mesenchymal stem cell therapies have not been tested in large-scale trials against them.
Knee cartilage damage left untreated and when repair helps
avatar
Miss Sophie Harris
12/8/2026
Knee cartilage damage left untreated and when repair helps
Cartilage lacks blood vessels, nerve fibres, and lymph channels, so repair cells cannot reach injuries and pain does not warn of damage, allowing lesions to expand silently until they become clinically serious.Cartilage lacks blood vessels, nerve fibres, and lymph channels, so repair cells cannot reach injuries and pain does not warn of damage, allowing lesions to expand silently until they become clinically serious.
OATS Mosaicplasty Knee Recovery Timeline
avatar
Miss Sophie Harris
11/8/2026
OATS Mosaicplasty Knee Recovery Timeline
Full recovery from OATS mosaicplasty spans 6–12 months, extending to 12–18 months for competitive sport, because transplanted bone-and-cartilage plugs require time for biological integration and graft maturation.Full recovery from OATS mosaicplasty spans 6–12 months, extending to 12–18 months for competitive sport, because transplanted bone-and-cartilage plugs require time for biological integration and graft maturation.
Ten-Year Success Rates for OATS Mosaicplasty
avatar
Miss Sophie Harris
9/8/2026
Ten-Year Success Rates for OATS Mosaicplasty
Ten-year success rates for OATS mosaicplasty span 72–89% in young, active patients; failure rates drop to 12.5–14% in optimal candidates (under 40, lesion under 3 cm²) but rise to 38–40% in older patients with larger defects.Ten-year success rates for OATS mosaicplasty span 72–89% in young, active patients; failure rates drop to 12.5–14% in optimal candidates (under 40, lesion under 3 cm²) but rise to 38–40% in older patients with larger defects.
Who qualifies for MACI knee surgery?
avatar
Miss Sophie Harris
8/8/2026
Who qualifies for MACI knee surgery?
Patients aged 18–55 with deep focal cartilage damage (Grade III-IV, >2 cm²) qualify for MACI if their knees are structurally sound—stable ligaments, correct alignment, no generalised osteoarthritis—and conservative treatment has failed. The procedure is two-stage, with extended rehabilitation required.Patients aged 18–55 with deep focal cartilage damage (Grade III-IV, >2 cm²) qualify for MACI if their knees are structurally sound—stable ligaments, correct alignment, no generalised osteoarthritis—and conservative treatment has failed. The procedure is two-stage, with extended rehabilitation required.
Cartilage specialist or general orthopaedic surgeon for a knee defect
avatar
Miss Sophie Harris
7/8/2026
Cartilage specialist or general orthopaedic surgeon for a knee defect
Knee cartilage repair without correcting underlying malalignment results in reoperation in 47.4% of cases, versus 17.3% when alignment is corrected simultaneously — a surgical integration that general orthopaedic surgeons often omit from initial assessment and planning.Knee cartilage repair without correcting underlying malalignment results in reoperation in 47.4% of cases, versus 17.3% when alignment is corrected simultaneously — a surgical integration that general orthopaedic surgeons often omit from initial assessment and planning.
Choosing between ACI and MACI for cartilage repair
avatar
Miss Sophie Harris
6/8/2026
Choosing between ACI and MACI for cartilage repair
MACI cartilage grafts show 90% fill at two years but decline to 49% by ten years; 73% become fibrocartilage rather than the hyaline cartilage needed for durability.MACI cartilage grafts show 90% fill at two years but decline to 49% by ten years; 73% become fibrocartilage rather than the hyaline cartilage needed for durability.
MACI recovery and return to sport
avatar
Miss Sophie Harris
4/8/2026
MACI recovery and return to sport
MACI recovery takes twelve to eighteen months before high-impact sport. Most patients return to some sport, but only one-third reach their pre-injury level — a gap significantly driven by kinesiophobia, which clinical teams can screen and address through sports psychology support.MACI recovery takes twelve to eighteen months before high-impact sport. Most patients return to some sport, but only one-third reach their pre-injury level — a gap significantly driven by kinesiophobia, which clinical teams can screen and address through sports psychology support.
When cartilage repair is the right choice
avatar
Miss Sophie Harris
2/8/2026
When cartilage repair is the right choice
Cartilage repair is only for younger, active patients with small focal defects who can sustain nine to eighteen months of intensive rehabilitation.Cartilage repair is only for younger, active patients with small focal defects who can sustain nine to eighteen months of intensive rehabilitation.
OATS versus osteochondral allograft for large knee defects
avatar
Miss Sophie Harris
1/8/2026
OATS versus osteochondral allograft for large knee defects
Defect size determines which procedure: OATS, harvesting cartilage plugs from the patient's own knee, suits lesions up to 4 cm²; osteochondral allograft, using donor tissue, handles larger defects without an equivalent size limit.Defect size determines which procedure: OATS, harvesting cartilage plugs from the patient's own knee, suits lesions up to 4 cm²; osteochondral allograft, using donor tissue, handles larger defects without an equivalent size limit.
OATS or MACI for mid-size knee cartilage defects
avatar
Miss Sophie Harris
31/7/2026
OATS or MACI for mid-size knee cartilage defects
Within the 2–4 cm² range, cartilage defects are large enough that a single plug fails to cover them, yet small enough that two repair techniques remain viable: osteochondral autograft restores cartilage and bone in one operation but creates coverage gaps, whilst matrix-induced autologous chondrocyte implantation requires two operations with laboratory…Within the 2–4 cm² range, cartilage defects are large enough that a single plug fails to cover them, yet small enough that two repair techniques remain viable: osteochondral autograft restores cartilage and bone in one operation but creates coverage gaps, whilst matrix-induced autologous chondrocyte implantation requires two operations with laboratory culture but accommodates irregular shapes without gaps.
Osteochondral Allograft for Post-Traumatic Knee Defects
avatar
Miss Sophie Harris
30/7/2026
Osteochondral Allograft for Post-Traumatic Knee Defects
Osteochondral allograft restores both the cartilage surface and the bone beneath in a single operation for post-traumatic knee injuries — a combination other procedures cannot deliver.Osteochondral allograft restores both the cartilage surface and the bone beneath in a single operation for post-traumatic knee injuries — a combination other procedures cannot deliver.
287 results found in 4ms