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171 results found in 4ms
When knee cartilage repair is worth considering
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Miss Sophie Harris
24/7/2026
When knee cartilage repair is worth considering
Cartilage lacks a blood supply and cannot self-heal, but surgical or minimally invasive repair can restore focal defects in otherwise healthy joints, potentially delaying knee replacement by years or decades.Cartilage lacks a blood supply and cannot self-heal, but surgical or minimally invasive repair can restore focal defects in otherwise healthy joints, potentially delaying knee replacement by years or decades.
OCA vs MACI for large knee cartilage defects
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Miss Sophie Harris
21/7/2026
OCA vs MACI for large knee cartilage defects
MACI (matrix-induced autologous chondrocyte implantation) is a surface repair requiring intact subchondral bone; osteochondral allograft (OCA) replaces both cartilage and bone. When knee cartilage defects breach underlying bone, OCA addresses what MACI cannot.MACI (matrix-induced autologous chondrocyte implantation) is a surface repair requiring intact subchondral bone; osteochondral allograft (OCA) replaces both cartilage and bone. When knee cartilage defects breach underlying bone, OCA addresses what MACI cannot.
AMIC vs MACI for knee cartilage repair
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Miss Sophie Harris
19/7/2026
AMIC vs MACI for knee cartilage repair
Standalone microfracture for knee cartilage defects has less than 60% survivorship at three years; AMIC adds a collagen membrane to stabilize repair, whilst MACI uses cultured chondrocytes and shows superiority in the SUMMIT trial for lesions over 3 cm².Standalone microfracture for knee cartilage defects has less than 60% survivorship at three years; AMIC adds a collagen membrane to stabilize repair, whilst MACI uses cultured chondrocytes and shows superiority in the SUMMIT trial for lesions over 3 cm².
How single-stage ACI differs from MACI
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Miss Sophie Harris
18/7/2026
How single-stage ACI differs from MACI
MACI repairs cartilage defects over two operations, with weeks between them for external cell expansion; STACi compresses the entire process—harvesting, processing, and implantation—into a single surgical session.MACI repairs cartilage defects over two operations, with weeks between them for external cell expansion; STACi compresses the entire process—harvesting, processing, and implantation—into a single surgical session.
ACI or MACI for knee cartilage repair
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Miss Sophie Harris
12/7/2026
ACI or MACI for knee cartilage repair
Both ACI and MACI require two operations: stage-1 biopsy yields too few chondrocytes for immediate repair, so stage-2 implantation must follow 3–6 weeks of laboratory expansion.Both ACI and MACI require two operations: stage-1 biopsy yields too few chondrocytes for immediate repair, so stage-2 implantation must follow 3–6 weeks of laboratory expansion.
When cartilage repair makes sense before knee replacement
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Miss Sophie Harris
10/7/2026
When cartilage repair makes sense before knee replacement
Total knee replacement achieves over 90% long-term success, yet patients under 55 face substantially higher revision risk within 20 years. For focal cartilage damage in the mid-40s, repair offers a joint-preservation pathway suited to this earlier disease stage—provided defect size and patient profile meet defined clinical criteria.Total knee replacement achieves over 90% long-term success, yet patients under 55 face substantially higher revision risk within 20 years. For focal cartilage damage in the mid-40s, repair offers a joint-preservation pathway suited to this earlier disease stage—provided defect size and patient profile meet defined clinical criteria.
OATS versus mosaicplasty for knee cartilage repair
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Miss Sophie Harris
9/7/2026
OATS versus mosaicplasty for knee cartilage repair
OATS and mosaicplasty are the same surgical technique applied at different scales: OATS transfers a single cartilage plug for knee defects under 2 cm², mosaicplasty tiles smaller grafts across 2–4 cm² lesions.OATS and mosaicplasty are the same surgical technique applied at different scales: OATS transfers a single cartilage plug for knee defects under 2 cm², mosaicplasty tiles smaller grafts across 2–4 cm² lesions.
OCA or MACI for large knee cartilage defects
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Miss Sophie Harris
8/7/2026
OCA or MACI for large knee cartilage defects
When subchondral bone is damaged alongside large knee cartilage defects, OCA — a single-stage transplant of donor bone and cartilage — is the preferred choice; MACI, which implants cultured cells, cannot restore bone stock once lost.When subchondral bone is damaged alongside large knee cartilage defects, OCA — a single-stage transplant of donor bone and cartilage — is the preferred choice; MACI, which implants cultured cells, cannot restore bone stock once lost.
Osteochondral Allograft for Post-Traumatic Knee Defects
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Miss Sophie Harris
7/7/2026
Osteochondral Allograft for Post-Traumatic Knee Defects
When post-traumatic knee injury damages both cartilage and underlying bone, osteochondral allograft transplants provide a single-stage solution that other repair methods cannot match. Roughly 75–82% of patients return to sport; grafts show 87% survival at five years, declining to 68% at twenty.When post-traumatic knee injury damages both cartilage and underlying bone, osteochondral allograft transplants provide a single-stage solution that other repair methods cannot match. Roughly 75–82% of patients return to sport; grafts show 87% survival at five years, declining to 68% at twenty.
MACI versus microfracture for knee cartilage repair
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Miss Sophie Harris
7/7/2026
MACI versus microfracture for knee cartilage repair
MACI outperforms microfracture for knee cartilage defects of 3 cm² or larger, according to the SUMMIT randomised trial, which found significantly greater improvements in pain and function at two years that persisted through five years.MACI outperforms microfracture for knee cartilage defects of 3 cm² or larger, according to the SUMMIT randomised trial, which found significantly greater improvements in pain and function at two years that persisted through five years.
AMIC vs microfracture for knee cartilage repair
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Miss Sophie Harris
5/7/2026
AMIC vs microfracture for knee cartilage repair
Both AMIC and microfracture improve pain and function in the first two years; beyond that point, microfracture outcomes progressively deteriorate whilst AMIC maintains stable gains through a decade of follow-up.Both AMIC and microfracture improve pain and function in the first two years; beyond that point, microfracture outcomes progressively deteriorate whilst AMIC maintains stable gains through a decade of follow-up.
ACI knee cartilage repair in the UK
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Miss Sophie Harris
4/7/2026
ACI knee cartilage repair in the UK
ACI harvests a patient's own cartilage cells, cultures them to roughly 20 times their original number, then implants them in a second operation; NHS funding applies only to patients with defects over 2 cm², no prior cartilage repair, minimal arthritis, and access to a specialist centre.ACI harvests a patient's own cartilage cells, cultures them to roughly 20 times their original number, then implants them in a second operation; NHS funding applies only to patients with defects over 2 cm², no prior cartilage repair, minimal arthritis, and access to a specialist centre.
171 results found in 4ms