How long osteochondral allografts laston patient BMI, priorkneesurgery, and adherence toon patient BMI, prior knee surgery, and adherence to
How defect size and age decide OATS or OCAfrom the patient's ownknee) or donor allograft (OCA):from the patient's own knee) or donor allograft (OCA):
High tibial osteotomy recovery and joint preservationaway from a damagedkneecompartment and is bestaway from a damaged knee compartment and is best
Can chondroplasty or an unloader brace helptrims and smooths damagedkneecartilage to ease catchingtrims and smooths damaged knee cartilage to ease catching
Conservative management for Bone Marrow Edema, Early stages of SONK (and PEMF)Spontaneous Osteonecrosis of theKnee(SONK) can severely affectSpontaneous Osteonecrosis of the Knee (SONK) can severely affect
Recovery After OATS for Ankle Cartilage Repairhealthy graft from theknee, producing hyaline-like tissue ratherhealthy graft from the knee, producing hyaline-like tissue rather
MACI Recovery From Six Weeks to Two YearsOnly a third of MACI patients return to their pre-operative sport level, despite most achieving pain-free function within six months and return to sport by 12–18 months. Kinesiophobia—fear of re-injury—emerges as a statistically significant independent predictor of this shortfall, distinct from tissue maturity.Only a third of MACI patients return to their pre-operative sport level, despite most achieving pain-free function within six months and return to sport by 12–18 months. Kinesiophobia—fear of re-injury—emerges as a statistically significant independent predictor of this shortfall, distinct from tissue maturity.
When cartilage repair is the right choiceCartilage repair is suited to younger, active patients with isolated damage in otherwise healthy joints where conservative care has not worked. It is mechanistically impossible when underlying bone is worn smooth, degeneration spans multiple compartments, or malalignment and instability persist uncorrected.Cartilage repair is suited to younger, active patients with isolated damage in otherwise healthy joints where conservative care has not worked. It is mechanistically impossible when underlying bone is worn smooth, degeneration spans multiple compartments, or malalignment and instability persist uncorrected.
Ten-Year Success Rates for OATS MosaicplastyTen-year success rates for OATS mosaicplasty span 72–89% in young, active patients; failure rates drop to 12.5–14% in optimal candidates (under 40, lesion under 3 cm²) but rise to 38–40% in older patients with larger defects.Ten-year success rates for OATS mosaicplasty span 72–89% in young, active patients; failure rates drop to 12.5–14% in optimal candidates (under 40, lesion under 3 cm²) but rise to 38–40% in older patients with larger defects.
Choosing between ACI and MACI for cartilage repairMACI cartilage grafts show 90% fill at two years but decline to 49% by ten years; 73% become fibrocartilage rather than the hyaline cartilage needed for durability.MACI cartilage grafts show 90% fill at two years but decline to 49% by ten years; 73% become fibrocartilage rather than the hyaline cartilage needed for durability.
MACI recovery and return to sportMACI recovery takes twelve to eighteen months before high-impact sport. Most patients return to some sport, but only one-third reach their pre-injury level — a gap significantly driven by kinesiophobia, which clinical teams can screen and address through sports psychology support.MACI recovery takes twelve to eighteen months before high-impact sport. Most patients return to some sport, but only one-third reach their pre-injury level — a gap significantly driven by kinesiophobia, which clinical teams can screen and address through sports psychology support.
Single-stage vs two-stage ACI for cartilage repairTraditional two-stage ACI involves two general anaesthetics separated by a four-to-six-week cell culture period; STACI performs both stages in a single theatre session, requiring one general anaesthetic and eliminating the inter-stage gap.Traditional two-stage ACI involves two general anaesthetics separated by a four-to-six-week cell culture period; STACI performs both stages in a single theatre session, requiring one general anaesthetic and eliminating the inter-stage gap.